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PREMPRO™/PREMARIN™
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Prempro FAQs
Welcome to
the Brown & Crouppen Prempro / Premarin page. Brown & Crouppen
is one of mid-America’s largest personal injury
litigators. We have been building our reputation for
legal success for almost a quarter of a century.
We have thrived
because of our
shared commitment to deliver the best possible
service to clients throughout Missouri and the
United States. Today, our team has grown to over 70 legal
professionals and five offices throughout Missouri
and Illinois. In recent years, the firm has seen a
surge in the number of clients suffering injury from
unsafe drugs. We
have successfully tackled the prescription drug
giants who make Rezulin™, Fen-Phen™, Lotronex™,
OxyContin™, Zyprexa™, PPA™, Ephedra, and
Prempro™.
Our firm’s skills, credentials and
resources have helped thousands of clients win
millions of dollars from the manufacturers and
suppliers of unsafe drugs and products.
Nationwide, there are
an estimated 6 million women taking the prescription
drug Prempro. Prempro is a leading Hormone
Replacement Therapy (HRT) drug that combines
estrogen and progestin into one pill. It is
prescribed to treat women experiencing menopausal
symptoms that include mood swings, hot flashes,
night sweats, vaginal dryness and osteoporosis.
When
first introduced, it was believed that HRT could
reduce the risk of osteoporosis and heart
complications in women. However, in July 2002, the
National Institute of Health (NIH) halted a major
clinical study of 16,000 women due to alarming
preliminary findings. The data suggested that after
only one year on Prempro, an otherwise healthy woman
faced increased risk of
- Heart attack (by
29%)
- Breast cancer (by
24%)
- Blood clots (by
200%)
- Stroke (by 41%).
- The National
Cancer Institute also reported in another study
that ovarian cancer risk in postmenopausal women
increased to 220% if they took estrogen for more
than 20 years.
For almost 40 years,
women have been encouraged to take drugs like
Prempro to relieve menopausal symptoms – yet these
drugs were recommended on unreliable medical
evidence. Wyeth pharmaceutical company, who is the
manufacturer of Prempro, has no plans to recall the
drug. Prempro bring almost $1.4 billion in revenue
to Wyeth’s coffer each year.
We believe that drug companies who place profit
above people must be held accountable for their
negligence and the damage they cause to innocent
victim’s lives.
In response to the Prempro controversy, Wyeth has issued new guidelines
that caution against long-term use and has reduced
the drug’s recommended dosage by half.
Unfortunately, it may be too little too late for the
many women who have suffered adverse effects. Unsafe
prescription drugs have been marketed without
comprehensive testing or have inadequate warning
labels. Even more alarming is the fact that many of
the tests required by the Food and Drug
Administration (who regulates the prescription drug
market) may be funded by the drug manufacturer.
If you, or someone
you know, has been treated using estrogen or a
combination of estrogen/progestin hormone
replacement therapy, we suggest contacting your
doctor immediately to discuss whether HRT is the
best course of treatment.
If you have suffered
harmful effects from Prempro such as breast cancer,
stroke or heart attack, you may be entitled to file
a legal claim against the drugs maker for negligence
in product labeling and marketing. Brown & Crouppen has represented many victims of defective
drugs, and as our client, you will be backed by a
team of legal professionals, medical experts and
investigators who are committed to ensuring that
your rights are protected.
Brown & Crouppen can help you make informed
decisions about your legal rights, so please call
Brown & Crouppen at
1-800-536-HELP for your free legal
consultation or save time with our online
Contact Form.
For additional HRT /
Prempro information,
click here.
What are the different types of hormone
therapies?
How many postmenopausal women take
estrogen alone or estrogen plus progestin therapy?
What is the important information about
Premarin and Prempro and all estrogens and estrogens plus
progestins drug products?
What are the dangers associated with
Prempro?
Are Premarin and Prempro safer in lower
doses?
Is it dangerous to abruptly stop HRT?
Should Prempro be stopped gradually? Will I bleed if I stop
taking Prempro?
Are there alternatives to HRT?
Are the estrogens and progestins in
birth control pills (oral
contraceptives) the same as those in Prempro
and Premarin? Do they have the same risks?
What are the different types of
hormone therapies?
There are a wide range of different hormone
therapies – patches and pills, natural and synthetic,
combinations of estrogen and progesterones, and
individual estrogen and progesterones. Prempro, Premarin,
Provera, Estrogen therapy... and each has its own risks
and potential benefits. Informing yourself of the
possible dangers is
important, and only you and your doctor can determine
the most effective and safe method of treatment.
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Therapy
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Terminology
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Newer
Terminology
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| Using
estrogen with or without progestin |
Hormone replacement therapy (HRT) |
Hormone therapy (HT) |
| Using
estrogen alone |
Estrogen replacement therapy (ERT) |
Estrogen therapy (ET) |
| Using
estrogen with a progestin |
Hormone replacement therapy (HRT) |
Estrogen-progestin therapy (EPT) |
How many postmenopausal women take
estrogen alone or estrogen plus progestin therapy?
Wyeth estimates that approximately 5 million U.S. women
are taking Premarin and 1.5 million are taking Prempro.
Approximately 10 million postmenopausal women are taking
some form of estrogen, either alone or in combination
with a progestin.
What is the important information
about Premarin and Prempro and all estrogens and
estrogens plus progestins drug products?
Premarin and Prempro, as well as other estrogen and
estrogen plus progestin drug products have associated
risks that may outweigh the benefits for women. A major
HRT study released by the Womens Health Initiative shows
(read study):
- Postmenopausal women should not take estrogen and
progestin to protect the heart.
- Estrogens and progestins may increase the risk of
heart attack, stroke, blood clots and breast cancer.
- Although other doses of Prempro and other
estrogens and progestins were not studied,
postmenopausal women who take estrogens and progestins
should also be warned about potential risks, which
must be presumed to be the same.
- When these drugs are being prescribed only to
prevent osteoporosis, other treatments should be
considered before prescribing estrogen or estrogen
with progestin.
- Estrogens and estrogens with progestins should be
used at the lowest dose for the shortest duration.
What are the dangers
associated with Prempro?
Study results show that for every 10,000 healthy,
postmenopausal women taking PremPro for a year, there
would be eight additional cases of breast cancer, seven
heart attacks, eight strokes and eight blood clots in
the lungs. At first glance, those numbers don’t seem
significant. However, in 2002, more than 6 million women
were taking PremPro. Statistically, that translates
into:
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480,000 additional breast cancer cases.
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420,000 more heart attacks.
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480,000 more strokes.
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480,000 more blood clot cases.
Study results on the effects of Prempro also show:
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26 percent increase in breast cancer.
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41 percent increase in strokes.
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29 percent increase in heart attacks.
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100 percent increase of blood clots in
legs and lungs.
Raising more red flags is the reported
increase in the incidence of ovarian cancer in WHI study
participants. Women who took estrogen HRTs for long
periods of time had a higher risk of developing the rare
form of cancer, and researchers noted a 7 percent
increase in risk associated with every extra year of
estrogen HRT use. Researchers called the trend
“worrisome.”
Are Premarin and
Prempro safer in lower doses?
The dose of Prempro used in the
WHI study was
0.625 mg, which is the same as 0.625 mg Premarin
(conjugated estrogens) plus 2.5 mg medroxyprogesterone
acetate (progestin). It is not known whether Premarin
and Prempro are safer in lower doses. Generally,
medicines should be used at the lowest effective dose.
The FDA cannot make further recommendations until
studies are performed using lower doses.
Is it dangerous to abruptly stop HRT?
Should Prempro be stopped gradually? Will I bleed if I
stop taking Prempro?
It is not dangerous to just stop your HRT. You may get
some minimal bleeding if you stop HRT, but that is not
dangerous. Your menopausal symptoms such as hot flashes
may return if you stop HRT.
Are there alternatives to HRT?
Absolutely, but it depends on what symptoms you are
treating or what diseases you are trying to prevent.
There are multiple herbal supplements that have been
found to help against hot flashes, such as black cohash.
There are excellent medications for the prevention and
treatment of osteoporosis. There are estrogen
medications that can be applied just to the vagina that
help treat vaginal dryness. Exercise and diet can also
go along way to prevent the side effects of menopause.
You should talk to your doctor about your symptoms and
the options available to you.
Learn more about
Prempro alternatives.
Are the estrogens and progestins in
birth control pills (oral contraceptives) the same as
those in Prempro and Premarin? Do they have the same
risks?
Oral contraceptives also contain estrogens and
progestins, but different types and doses. All estrogens
have similar side effects. However, the risks of
particular side effects may differ since oral
contraceptives are used in younger women with different
health status compared to postmenopausal women.
As with all estrogens, the use of oral contraceptives is
also associated with increased risks of several serious
conditions including heart attack, blood clots, stroke,
liver tumors, and gallbladder disease. These risks are
higher in women with underlying risk factors such as
high blood pressure, high cholesterol, and diabetes, and
in those who smoke cigarettes.
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My name is Ron Brown,
along with my partner Terry Crouppen we founded
Brown and Crouppen almost 20 years ago. Today, we
are proud to say that we are one of mid-America’s
largest personal injury law firms. For some time now
we have concentrated a lot of our time and resources
in the area of dangerous drug litigation. We have
partnered with some of the country’s best drug
litigation specialists to create a legal team we
feel is second to none.
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It’s
really terrible to read about a prescription drug
being recalled because of dangerous side effects,
when you’re one of the people taking it. That’s what
happened to me a few years ago. I suffer from a
chronic disease and my doctor prescribed a drug to
help me manage it better. After being on the drug
for a while I began to feel weak and reported it to
my doctor. I can’t say enough good things about him,
he saved my life. He realized that my problems were
being caused not by my disease but by the
prescription drug that was supposed to be helping
me.
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A lot of people
believe that the giant corporations of the world are
impossible to beat. Let me assure you this is not
true. Everyday, Brown and Crouppen as well as other
prominent law firms across America take on these
giants and win. The real wonder of the American
legal system is that it allows individuals to
litigate important matters against giant
corporations as equals. If a case has merit our
system enables you to win compensation for the harm
done. It happens everyday.
CONTINUE |
Learn more about other dangerous
pharmaceutical drugs and pharmaceutical negligence:
Call Brown & Crouppen at
1-800-536-HELP
for your free legal consultation or save time with
our online
Contact Form.
1-800-536-HELP |
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SITE MAP | Copyright
© - Brown & Crouppen, P.C., Attorneys at Law,
St. Louis, Missouri -
Fairview Heights, Illinois. Injury Lawyers in MO & IL.
All Rights Reserved. Concentrating In
Personal Injury Accidents & Disability, Including Medical
Malpractice, Work Related Injuries,
Dangerous Drugs & Devices, Harmful
Chemical Exposure,
and Financial Matters -
Neurontin Lawyers,
Oxycontin,
Prempro HRT Attorneys.
Serving Crawford, Franklin, Gasconade, Iron,
Jefferson, Lincoln, Pike, St.
Charles, St. Francois, St. Genevieve, St. Louis, Warren, Washington
Missouri & Illinois Counties.
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